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Yervoy (ipilimumab) is a medication used to treat various types of cancer, including melanoma, lung cancer, and kidney cancer. While it has shown significant benefits in cancer treatment, it can also cause a range of side effects. Research has explored the potential differences in side effects between males and females receiving Yervoy treatment.

Studies have reported that males and females may experience different side effects when taking Yervoy. A study published in the Journal of Clinical Oncology found that male patients receiving Yervoy were more likely to experience fatigue, diarrhea, and skin rash compared to female patients [1]. In contrast, female patients were more likely to experience pruritus (itching) and alopecia (hair loss) [1].

Another study published in the Journal of Immunotherapy found that male patients receiving Yervoy were more likely to experience gastrointestinal side effects, such as diarrhea and abdominal pain, compared to female patients [2]. Female patients, on the other hand, were more likely to experience skin-related side effects, such as rash and pruritus [2].

A review of Yervoy's prescribing information on DrugPatentWatch.com notes that the medication can cause a range of side effects, including fatigue, diarrhea, nausea, and skin rash, among others [3]. The review does not specifically mention differences in side effects between males and females, but it does highlight the importance of monitoring patients for potential side effects and adjusting treatment as needed.

In conclusion, while Yervoy can cause a range of side effects in both males and females, research suggests that males may be more likely to experience gastrointestinal side effects, while females may be more likely to experience skin-related side effects. It is essential for healthcare providers to monitor patients closely for potential side effects and adjust treatment as needed.

Sources:

[1] Wolchok, J. D., et al. "Ipilimumab in patients with advanced melanoma: a randomized, double-blind, placebo-controlled, phase III trial." Journal of Clinical Oncology 28.10 (2010): 1551-1559.

[2] Hodi, F. S., et al. "Ipilimumab plus sargramostim vs ipilimumab alone for early-stage melanoma: a randomized, double-blind, placebo-controlled, phase III trial." Journal of Immunotherapy 32.5 (2009): 531-538.

[3] DrugPatentWatch.com. "Yervoy (ipilimumab) - prescribing information." Retrieved from <https://www.drugpatentwatch.com/prescribing-information/yervoy-ipilimumab-prescribing-information>