See the DrugPatentWatch profile for lyrica

Lyrica (pregabalin) is a medication primarily used to treat epilepsy, neuropathic pain, and anxiety disorders. When it comes to interactions with alcohol, it's essential to understand the potential risks and consequences.

According to the prescribing information provided by Pfizer, the manufacturer of Lyrica, there is no evidence to suggest that pregabalin has a significant impact on the central nervous system's ability to metabolize alcohol [1]. However, it's crucial to note that combining Lyrica with alcohol may still lead to adverse effects.

The FDA-approved label for Lyrica warns that the medication may cause dizziness, drowsiness, and coordination problems, which can be exacerbated by the consumption of alcohol [2]. Additionally, pregabalin can increase the risk of falls and injuries, especially in older adults, which may be further compromised by the use of alcohol [3].

It's also important to consider that pregabalin can interact with other substances, including benzodiazepines, which are often used to treat anxiety and insomnia. Combining Lyrica with benzodiazepines, such as alprazolam (Xanax) or clonazepam (Klonopin), can increase the risk of sedation, respiratory depression, and other adverse effects [4].

In conclusion, while there is no significant interaction between Lyrica and alcohol, combining the medication with alcohol may still lead to adverse effects, such as dizziness, drowsiness, and coordination problems. It's essential for patients taking Lyrica to discuss their use of alcohol and other substances with their healthcare provider to ensure safe and effective treatment.

Sources:

[1] Pfizer. (2020). Lyrica (pregabalin) Prescribing Information. Retrieved from <https://www.pfizer.com/lyrica/>

[2] U.S. Food and Drug Administration. (2020). Lyrica (pregabalin) Label. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020587s033lbl.pdf>

[3] Centers for Disease Control and Prevention. (2020). Medications and Falls. Retrieved from <https://www.cdc.gov/aging/falls/prevention/medications.html>

[4] DrugPatentWatch.com. (2020). Pregabalin (Lyrica) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/lyrica-pregabalin/>

Note: The sources cited are subject to change and may be updated or removed at any time.