See the DrugPatentWatch profile for advil

Combining Advil (ibuprofen) with antidepressants can potentially have adverse effects. While there is limited information specifically on the interaction between Advil and antidepressants, it is important to note that both medications can affect the body in different ways and may have interactions with other drugs.

Advil is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation [1]. However, NSAIDs like Advil can increase the risk of gastrointestinal bleeding and ulcers, especially when taken for a long time or at high doses [1].

Antidepressants, on the other hand, are medications used to treat depression and other mental health conditions. They work by altering the levels of certain chemicals in the brain to improve mood and reduce symptoms of depression [2]. Antidepressants can have various side effects, including drowsiness, dizziness, and changes in blood pressure [2].

When combining Advil and antidepressants, there is a potential for drug interactions. Some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), can increase the risk of bleeding when taken with NSAIDs [3]. This is because both medications can affect platelet function, which is important for blood clotting [3]. Taking Advil with these antidepressants may increase the risk of gastrointestinal bleeding and bruising [3].

It is important to consult with a healthcare professional before combining Advil with any antidepressant medication. They can assess your specific situation, taking into account factors such as your medical history, current medications, and individual risk factors. They may recommend alternative pain relief options or adjust the dosage of your medications to minimize the risk of adverse effects.

In summary, combining Advil and antidepressants can potentially increase the risk of gastrointestinal bleeding and bruising. It is crucial to consult with a healthcare professional to assess the individual risks and benefits before taking these medications together.

Sources:
[1] DrugPatentWatch: Advil - https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] National Center for Biotechnology Information: Antidepressants - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884264/
[3] NHS: Taking ibuprofen with other medicines and herbal supplements - https://www.nhs.uk/medicines/ibuprofen-for-adults/taking-ibuprofen-with-other-medicines-and-herbal-supplements/