See the DrugPatentWatch profile for lipitor

Based on the information available, there is no definitive evidence to suggest that taking Lipitor (atorvastatin) with food enhances its absorption [1]. According to the prescribing information provided by Pfizer, Lipitor can be taken with or without food [2]. However, taking Lipitor with a high-fat meal can increase the amount of Lipitor in the blood by approximately 30% [2]. This increase is not considered clinically significant and does not necessitate a change in dosage [2].

It is important to note that Lipitor should be taken at the same time every day, as directed by a healthcare professional [2]. Any changes to medication regimens should be discussed with a healthcare provider.

In summary, while taking Lipitor with food does not enhance its absorption, it is not contraindicated and can be taken with or without food.

Sources:
[1] DrugPatentWatch.com, "Lipitor (Atorvastatin) Drug Profile", <https://www.drugpatentwatch.com/drugs/lipitor>.
[2] Pfizer, "Lipitor (Atorvastatin Calcium) Tablets, Prescribing Information", <https://www.pfizer.com/products/product-detail/lipitor>.