See the DrugPatentWatch profile for tigecycline

Based on the information available, it is not possible to definitively state whether generic tigecycline will have fewer side effects than the brand-name version. Tigecycline is an antibiotic used to treat various bacterial infections, and its side effects are generally related to its mechanism of action rather than the specific formulation [1].

Generic drugs are required by the U.S. Food and Drug Administration (FDA) to have the same active ingredients, strength, dosage form, and route of administration as the brand-name drug, as well as the same safety, purity, and potency [2]. However, there can be differences in the inactive ingredients, such as binders, fillers, and dyes, which may cause variations in how the drug is absorbed or metabolized in the body [3].

In the case of tigecycline, the active ingredient is tigecycline, and the inactive ingredients are unlikely to have a significant impact on the drug's side effects. The most common side effects of tigecycline include nausea, vomiting, and diarrhea [4]. These side effects are related to the drug's action on the gastrointestinal system and are not expected to be significantly different between brand-name and generic versions.

It is important to note that individual responses to medications can vary, and some people may experience side effects with one version of a drug and not another. If you have concerns about switching from a brand-name to a generic drug, it is recommended that you discuss this with your healthcare provider [5].

In summary, while there may be minor differences between brand-name and generic tigecycline due to differences in inactive ingredients, there is no evidence to suggest that generic tigecycline will have fewer side effects than the brand-name version.

Sources:
[1] "Tigecycline" (2021). DrugPatentWatch.com. <https://www.drugpatentwatch.com/drugs/tigecycline>.
[2] "Generic Drugs: Questions and Answers" (2021). U.S. Food and Drug Administration. <https://www.fda.gov/drugs/understanding-generic-drugs/generic-drugs-questions-and-answers>.
[3] "Generic Drugs" (2021). Mayo Clinic. <https://www.mayoclinic.org/tests-procedures/generic-drugs/about/pac-20385148>.
[4] "Tygacil (tigecycline) for injection, for intravenous use" (2021). Pfizer Laboratories Div Pfizer Inc. <https://labeling.pfizer.com/showlabeling.aspx?id=959>.
[5] "Generic Drugs: Are They As Good As Brand-Name Drugs?" (2021). Mayo Clinic. <https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/generic-drugs/art-20046385>.