See the DrugPatentWatch profile for probenecid

Probenecid is a medication that can affect the absorption of other drugs by decreasing their excretion by the kidneys [1]. However, according to the information available, there is no specific interaction between probenecid and tigecycline that would suggest probenecid alters tigecycline's absorption [2].

Tigecycline is an antibiotic that is not significantly metabolized by the liver and is primarily excreted unchanged by the kidneys [3]. The drug label for tigecycline does not list probenecid as a drug that affects its absorption or excretion [4].

It is important to note that while probenecid can affect the absorption and excretion of some drugs, it does not have a known interaction with tigecycline. However, as with any medication, it is always important to consult with a healthcare provider or pharmacist before starting or stopping any medications, including probenecid and tigecycline.

Sources:

1. U.S. National Library of Medicine. (2021). Probenecid. MedlinePlus. <https://medlineplus.gov/druginfo/meds/a682015.html>
2. Drugs.com. (2021). Tigecycline Drug Interactions. <https://www.drugs.com/drug-interactions/tigecycline,probencid,1262-2255-1581-0.html>
3. U.S. Food and Drug Administration. (2010). TIGASYC (tigecycline) for injection, for intravenous use. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021927s015lbl.pdf>
4. DrugPatentWatch. (n.d.). Tigecycline. <https://www.drugpatentwatch.com/drugs/tigecycline>