See the DrugPatentWatch profile for methotrexate

Methotrexate is a medication used to treat certain types of cancer, rheumatoid arthritis, and severe psoriasis, according to Mayo Clinic [1]. Due to its potency and potential side effects, it is crucial to take specific precautions when using methotrexate.

1. Consult your healthcare provider: Before starting methotrexate, inform your healthcare provider about your medical history, current medications, and any allergies [1]. This will help them determine if methotrexate is the right treatment for you.

2. Follow dosage instructions: Take methotrexate exactly as prescribed by your healthcare provider, and do not alter the dosage without consulting them first [1]. Overdosing can lead to severe side effects.

3. Monitor liver function: Methotrexate can affect liver function, so regular monitoring through blood tests is essential, especially if you have a history of liver disease or consume alcohol regularly [1].

4. Avoid pregnancy and breastfeeding: Methotrexate can cause birth defects or miscarriage. Therefore, women should avoid becoming pregnant while taking methotrexate and for at least six months after the last dose [1]. Men should also avoid fathering a child while taking methotrexate and for at least three months after the last dose [1]. Additionally, methotrexate passes into breast milk and can harm a breastfeeding infant, so it is recommended to avoid breastfeeding while taking this medication [1].

5. Limit alcohol consumption: Alcohol can increase the risk of liver damage when taking methotrexate [1]. Limit or avoid alcohol consumption during treatment.

6. Manage infections: Methotrexate can lower your body's ability to fight infections. Notify your healthcare provider if you experience signs of infection, such as fever, chills, or sore throat [1].

7. Be cautious with other medications: Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with methotrexate [1].

8. Regular check-ups: Schedule regular appointments with your healthcare provider to monitor your health and the effectiveness of methotrexate [1].

For more information on methotrexate and its patents, consult DrugPatentWatch.com [2].

Sources:
[1] Mayo Clinic. (2021). Methotrexate (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/methotrexate-oral-route/description/drg-20062731>
[2] DrugPatentWatch.com. (n.d.). Methotrexate. Retrieved from <https://www.drugpatentwatch.com/drugs/methotrexate>