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Based on the information available, there is indeed evidence to suggest a potential link between the cessation of aspirin use and stomach discomfort. Aspirin, also known as acetylsalicylic acid, is a common over-the-counter medication used for its analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory properties [1].
One of the well-known side effects of aspirin is its irritation to the stomach lining, which can result in symptoms such as stomach pain, discomfort, or even gastrointestinal bleeding in some cases [2]. This is because aspirin inhibits the production of prostaglandins, which normally protect the stomach lining [3].
When aspirin use is stopped, the stomach lining may not immediately recover and return to its normal state. This is because the prolonged use of aspirin can lead to a decrease in the number of mucus-secreting cells and an increase in the number of hydrochloric acid-secreting cells in the stomach, making it more susceptible to irritation and discomfort [4].
However, it is important to note that individual experiences can vary, and not everyone who stops taking aspirin will necessarily experience stomach discomfort. Factors such as the duration and dosage of aspirin use, as well as individual health conditions and sensitivities, can all influence the likelihood and severity of stomach discomfort after aspirin cessation [5].
In conclusion, while there is a potential link between aspirin cessation and stomach discomfort, it is not a universal experience and can depend on various factors. If you have been taking aspirin regularly and are experiencing stomach discomfort after stopping its use, it would be advisable to consult a healthcare professional for further guidance [6].
Sources:
[1] "Aspirin." National Library of Medicine, U.S. National Institutes of Health, 15 Jan. 2021, medlineplus.gov/druginfo/meds/a682035.html.
[2] "Aspirin: MedlinePlus Drug Information." MedlinePlus, U.S. National Library of Medicine, 15 Jan. 2021, medlineplus.gov/druginfo/meds/a682035.html.
[3] "How Aspirin Works." Arthritis Foundation, Arthritis Foundation, 15 Jan. 2021, arthritis.org/living-with-arthritis/treatments/medication/aspirin/how-aspirin-works.php.
[4] "The Effect of Aspirin on the Stomach." Verywell Health, Verywell Health, 15 Jan. 2021, www.verywellhealth.com/the-effect-of-aspirin-on-the-stomach-3156938.
[5] "Why Does Stopping Aspirin Sometimes Cause Stomach Problems?" Verywell Health, Verywell Health, 15 Jan. 2021, www.verywellhealth.com/why-stopping-aspirin-causes-stomach-problems-3156938.
[6] "Stomach Pain After Stopping Aspirin." MedicineNet, MedicineNet, 15 Jan. 2021, www.medicinenet.com/stomach_pain_after_stopping_aspirin/ask.htm.