See the DrugPatentWatch profile for cosentyx
Based on the information available, there is no definitive answer as to whether the vaccination schedule should be updated before starting Cosentyx therapy. However, it is important to note that certain vaccines may be less effective if given during or immediately after immunosuppressive therapy, such as Cosentyx [1].
Cosentyx (secukinumab) is a medication used to treat several conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [2]. It is a type of drug called a monoclonal antibody, which works by targeting and blocking a specific protein in the body that causes inflammation [3].
The Centers for Disease Control and Prevention (CDC) recommends that individuals consult with their healthcare provider to discuss their vaccination history and current immunization status before starting immunosuppressive therapy [4]. This is because some vaccines may not be recommended during or immediately after immunosuppressive therapy due to the potential for a reduced immune response [4].
In addition, the manufacturer of Cosentyx recommends that live vaccines be completed at least 4 weeks before starting Cosentyx therapy, and that live vaccines be avoided during Cosentyx treatment [5]. However, inactivated vaccines may be given at any time during Cosentyx therapy [5].
It is important to consult with a healthcare provider to determine the most appropriate vaccination schedule before starting Cosentyx therapy.
Sources:
[1] Cosentyx (secukinumab) [Prescribing Information]. Novartis Pharmaceuticals Corporation; 2021. Available at: <
https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf>.
[2] Cosentyx.com. Novartis. Available at: <
https://www.cosentyx.com/>.
[3] MedlinePlus. Secukinumab. Available at: <
https://medlineplus.gov/druginfo/meds/a616042.html>.
[4] Centers for Disease Control and Prevention. General Best Practice Guidelines for Immunization: Best Practices Guidance of the Advisory Committee on Immunization Practices (ACIP). Available at: <
https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/index.html>.
[5] Cosentyx (secukinumab) [Prescribing Information]. Novartis Pharmaceuticals Corporation; 2021. Available at: <
https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf>.
Additional source:
DrugPatentWatch.com. Secukinumab. Available at: <
https://www.drugpatentwatch.com/drugs/secukinumab>.