See the DrugPatentWatch profile for advil

Yes, there are alternatives to Advil that are less likely to upset your stomach. Advil, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that can cause stomach irritation, ulcers, and other gastrointestinal side effects in some people [1]. Here are a few alternatives:

1. Acetaminophen (Tylenol): Acetaminophen is a pain reliever and fever reducer that is generally gentler on the stomach than NSAIDs like Advil [2]. However, it is important to note that acetaminophen can cause liver damage if taken in excessive amounts.

2. Naproxen (Aleve): Naproxen is another NSAID, but it tends to be longer-acting and may cause fewer stomach problems than ibuprofen [3]. However, like all NSAIDs, naproxen can increase the risk of heart attack, stroke, and serious gastrointestinal side effects, especially in higher doses or with long-term use.

3. Celecoxib (Celebrex): Celecoxib is a type of NSAID called a COX-2 inhibitor, which specifically targets the enzyme that causes inflammation and pain [4]. Celecoxib is less likely to cause stomach irritation than other NSAIDs, but it still carries a risk of serious cardiovascular and gastrointestinal side effects.

4. Topical NSAIDs: Topical NSAIDs, such as creams, gels, or patches, can be applied directly to the site of pain and may cause fewer stomach problems than oral NSAIDs [5]. Examples include diclofenac (Voltaren) and ibuprofen (Icy Hot).

5. Natural alternatives: Some natural remedies, such as turmeric, ginger, and willow bark, have anti-inflammatory properties and may help relieve pain and inflammation [6]. However, it is important to talk to your doctor before trying any natural remedies, as they can interact with other medications and may not be safe for everyone.

It is important to note that while these alternatives may be easier on the stomach than Advil, they still carry risks and should be used with caution. Always follow the recommended dosage and talk to your doctor before starting any new medication.

Sources:

1. Mayo Clinic. Ibuprofen (Oral Route). <https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/side-effects/drg-20069386>.
2. Mayo Clinic. Acetaminophen (Oral Route). <https://www.mayoclinic.org/drugs-supplements/acetaminophen-oral-route/side-effects/drg-20068782>.
3. Mayo Clinic. Naproxen (Oral Route). <https://www.mayoclinic.org/drugs-supplements/naproxen-oral-route/side-effects/drg-20063491>.
4. Mayo Clinic. Celecoxib (Oral Route). <https://www.mayoclinic.org/drugs-supplements/celecoxib-oral-route/side-effects/drg-20062834>.
5. Mayo Clinic. Topical Nonsteroidal Anti-inflammatory Drugs (Topical NSAIDs). <https://www.mayoclinic.org/diseases-conditions/arthritis/in-depth/arthritis/art-20046441>.
6. Arthritis Foundation. Natural Remedies for Arthritis Pain. <https://www.arthritis.org/health-wellness/treatment/complementary-therapies/natural-remedies/natural-remedies-for-arthritis-pain>.

Additional source:

DrugPatentWatch.com. Ibuprofen. <https://www.drugpatentwatch.com/drugs/ibuprofen>.