See the DrugPatentWatch profile for tigecycline

Tigecycline is a broad-spectrum antibiotic, often used to treat various bacterial infections. One of the potential side effects of tigecycline is an elevation in liver enzymes. However, the frequency of this occurrence is not explicitly stated in the available information.

The prescribing information for tigecycline, available on DrugPatentWatch.com [1], lists liver enzyme elevations as a possible side effect. Still, it does not provide specific data on the frequency of this occurrence. The lack of specificity in the prescribing information suggests that liver enzyme elevations are not a common side effect, but it is not possible to determine the exact incidence rate based on the provided information.

In a study published in the Journal of Antimicrobial Chemotherapy [2], liver enzyme elevations were reported in some patients treated with tigecycline. However, the study did not provide a comprehensive analysis of the frequency of this side effect.

In summary, while liver enzyme elevations can occur with tigecycline use, the exact frequency of this occurrence is not explicitly stated in the available information. Healthcare professionals should monitor liver function in patients receiving tigecycline, as with any medication that carries the potential for liver enzyme elevations.

Sources:
[1] Wyeth Pharmaceuticals Inc., Tigecycline, Prescribing Information, accessed on DrugPatentWatch.com, <https://drugpatentwatch.com/drugs/tigecycline>.
[2] Karlowsky, J. A., et al., "Tigecycline: a review of its use in the treatment of complicated skin and soft tissue infections and complicated intra-abdominal infections," Journal of Antimicrobial Chemotherapy, vol. 63, no. 5, pp. 815-830, 2009.