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Based on the available information, it is possible for fatty foods to negate the cholesterol-lowering effect of Lipitor (atorvastatin). Lipitor is a medication used to treat high cholesterol levels by reducing the production of cholesterol in the body [1]. However, consuming fatty foods can increase cholesterol levels in the body, potentially counteracting the effects of Lipitor [2].

It is important to note that a balanced diet and regular exercise are crucial components of managing high cholesterol levels, in addition to medication [3]. Therefore, it is recommended to follow a heart-healthy diet, low in saturated and trans fats, and high in fruits, vegetables, and whole grains [4].

In conclusion, while Lipitor can effectively lower cholesterol levels, consuming fatty foods can negate its effects. Therefore, it is essential to maintain a healthy lifestyle, including a balanced diet, regular exercise, and medication as prescribed by a healthcare professional.

Sources:

1. "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 16 Feb. 2022, medlineplus.gov/druginfo/meds/a601249.html.
2. "Foods to Avoid If You Have High Cholesterol." Mayo Clinic, Mayo Foundation for Medical Education and Research, 11 Nov. 2021, [www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/high-cholesterol/art-20045192](http://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/high-cholesterol/art-20045192).
3. "High Cholesterol." National Heart, Lung, and Blood Institute, U.S. Department of Health and Human Services, 22 Feb. 2022, www.nhlbi.nih.gov/health-topics/high-blood-cholesterol.
4. "Dietary Fats." American Heart Association, 20 Jan. 2022, www.heart.org/en/healthy-living/healthy-eating/eat-smart/fats/dietary-fats.