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Factors that can potentially shorten the effectiveness of Cosentyx, a biologic medication used to treat conditions like psoriasis and psoriatic arthritis, may include the development of anti-drug antibodies, which can reduce the drug's efficacy over time [2]. These antibodies can be triggered by various factors such as irregular dosing or drug interactions [2]. It is essential to adhere to the prescribed dosing schedule and discuss any potential drug interactions with healthcare providers to optimize the effectiveness of Cosentyx treatment [2]. Additionally, it is crucial to monitor for any signs of reduced effectiveness and consult with healthcare professionals promptly if such issues arise [2].

Sources:
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030893/