See the DrugPatentWatch profile for lipitor

When considering the interaction between Lipitor (atorvastatin) and NSAIDs (non-steroidal anti-inflammatory drugs), it is important to be aware of potential effects on patients. According to available information, one common interaction involves an increased risk of muscle damage, known as rhabdomyolysis [1].

Rhabdomyolysis is a serious condition that can lead to kidney damage and other complications [1]. Symptoms of rhabdomyolysis include muscle pain, weakness, and dark or cola-colored urine [1].

It is important to note that not all NSAIDs have been shown to interact with Lipitor in this way. However, some NSAIDs, such as ibuprofen and naproxen, have been associated with an increased risk of rhabdomyolysis when taken with Lipitor [1].

Patients taking Lipitor and NSAIDs should be closely monitored for signs of muscle damage, and healthcare providers should consider alternative pain management options when possible [1].

In addition, it is important for patients to inform their healthcare providers of all medications they are taking, including over-the-counter medications and dietary supplements, to help prevent potential drug interactions [2].

Sources:

1. DrugPatentWatch.com. (n.d.). Atorvastatin (trade name Lipitor) - DrugPatentWatch. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin/>
2. Mayo Clinic. (2021, September 24). NSAIDs: Safe use for arthritis. Mayo Clinic. Retrieved from <https://www.mayoclinic.org/diseases-conditions/arthritis/in-depth/nsaids/art-20048293>