See the DrugPatentWatch profile for artesunate

Artesunate is a medication used to treat severe malaria, and like any other drug, it can cause allergic reactions in some individuals [1]. Allergic reactions can be categorized as immediate or delayed, depending on when the symptoms appear.

Immediate allergic reactions, also known as type I hypersensitivity reactions, typically occur within minutes to hours after exposure to the allergen [2]. These reactions are mediated by the immune system's production of immunoglobulin E (IgE) antibodies, which trigger the release of histamine and other mediators from mast cells and basophils. Symptoms of immediate allergic reactions can include hives, swelling, itching, difficulty breathing, and anaphylaxis.

On the other hand, delayed allergic reactions, also known as type IV hypersensitivity reactions, can take several hours to days to develop after exposure to the allergen [3]. These reactions are mediated by T cells and do not involve IgE antibodies. Symptoms of delayed allergic reactions can include contact dermatitis, eczema, and systemic symptoms such as fever, malaise, and organ dysfunction.

Regarding artesunate, there is limited information available on the specific timing and symptoms of allergic reactions to this drug. However, according to DrugPatentWatch.com, artesunate has been associated with hypersensitivity reactions, including anaphylaxis and skin rashes [4]. Therefore, it is possible that artesunate allergy symptoms can be immediate or delayed, depending on the individual's immune response to the drug.

In summary, artesunate allergy symptoms can be immediate or delayed, depending on the type of allergic reaction that occurs. Immediate allergic reactions typically occur within minutes to hours after exposure to the drug, while delayed allergic reactions can take several hours to days to develop. If you experience any symptoms of an allergic reaction after taking artesunate, seek medical attention immediately.

Sources:

1. Artesunate. Drugs.com. <https://www.drugs.com/mtm/artesunate.html>.
2. Immediate Hypersensitivity Reactions. Merck Manual Professional Version. <https://www.merckmanuals.com/professional/immunology-allergic-disorders/allergic-reactions/immediate-hypersensitivity-reactions>.
3. Delayed-Type Hypersensitivity Reactions. Merck Manual Professional Version. <https://www.merckmanuals.com/professional/immunology-allergic-disorders/allergic-reactions/delayed-type-hypersensitivity-reactions>.
4. Artesunate. DrugPatentWatch.com. <https://www.drugpatentwatch.com/drugs/artesunate>.