See the DrugPatentWatch profile for cosentyx

When considering live vaccines during Cosentyx (secukinumab) therapy, it is crucial to take certain precautions to ensure safety and treatment efficacy. Cosentyx is a medication used to treat various conditions such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. It is a monoclonal antibody that targets interleukin-17A (IL-17A), a cytokine involved in inflammatory and immune responses [1].

Live vaccines contain weakened but live viruses or bacteria, which can potentially cause infections in individuals with weakened immune systems [2]. Since Cosentyx affects the immune system, patients undergoing this therapy might be at an increased risk of developing infections from live vaccines [1].

Here are the recommended precautions when dealing with live vaccines during Cosentyx therapy:

1. Consult your healthcare provider: Discuss your vaccination history and future plans with your healthcare provider before starting Cosentyx therapy [1]. They can provide personalized advice based on your medical condition and treatment plan.

2. Avoid live vaccines: If possible, avoid receiving live vaccines during Cosentyx therapy [1]. Live vaccines include, but are not limited to, measles, mumps, and rubella (MMR) vaccine, varicella (chickenpox) vaccine, and oral poliovirus vaccine [2].

3. Defer Cosentyx therapy: If you require a live vaccine, your healthcare provider might recommend postponing Cosentyx therapy until after the vaccine has taken effect [1]. The exact duration may vary depending on the vaccine and individual circumstances.

4. Monitor for infections: During Cosentyx therapy, be vigilant for signs of infection, such as fever, fatigue, or swollen lymph nodes [1]. Inform your healthcare provider immediately if you experience any symptoms.

5. Maintain a healthy lifestyle: To support your immune system, follow a healthy lifestyle, including a balanced diet, regular exercise, adequate sleep, and stress management [1].

Sources:

1. Cosentyx (secukinumab) [Prescribing Information]. Novartis Pharmaceuticals Corporation; 2021. <https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf>
2. Centers for Disease Control and Prevention. Who Should Not Get Certain Vaccines? <https://www.cdc.gov/vaccines/vpd/vaccines-who-not-recommended.html>
3. DrugPatentWatch. Cosentyx (secukinumab) Drug Profile. <https://www.drugpatentwatch.com/drugs/cosentyx>