See the DrugPatentWatch profile for vascepa

Based on the information available, taking Vascepa with food is not expected to significantly affect its effectiveness. Vascepa, a prescription medication, contains the active ingredient icosapent ethyl, which is a form of omega-3 fatty acid [1]. According to the drug's prescribing information, Vascepa can be taken with or without food [2].

A study published in the Journal of Clinical Lipidology investigated the effect of food on the absorption of icosapent ethyl. The results showed that taking icosapent ethyl with a high-fat meal increased the drug's maximum concentration (Cmax) by 16% and the area under the curve (AUC) by 13% compared to fasting conditions. However, these differences were not statistically significant, suggesting that food has a minimal impact on the absorption and bioavailability of icosapent ethyl [3].

In summary, based on the available information from DrugPatentWatch.com and the cited study, taking Vascepa with food is not expected to have a clinically relevant impact on its effectiveness [1, 3]. As with any medication, it is always best to follow the specific dosing instructions provided by a healthcare professional.

Sources:

1. [DrugPatentWatch.com - Vascepa](https://www.drugpatentwatch.com/drugs/vascepa)
2. [Vascepa (icosapent ethyl) capsules, for oral use - prescribing information](https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/205677s000lbl.pdf)
3. [Effect of food on the bioavailability of icosapent ethyl (IPE) in healthy subjects - Journal of Clinical Lipidology](https://www.sciencedirect.com/science/article/pii/S1933287417310333)