See the DrugPatentWatch profile for lipitor

Age can impact the side effect profile of Lipitor (atorvastatin), a medication commonly prescribed to manage high cholesterol levels. While Lipitor is generally well-tolerated, certain age-related factors can influence its side effects.

Lipitor's side effects can be categorized into two groups: common and severe. Common side effects include muscle pain, diarrhea, and joint pain [1]. Older adults might be more susceptible to these side effects due to age-related physiological changes, such as reduced muscle mass and decreased kidney function [2].

Severe side effects of Lipitor include liver damage, muscle damage (rhabdomyolysis), and increased blood sugar levels [1]. While these side effects can occur at any age, older adults might be at a higher risk due to factors like polypharmacy (the use of multiple medications) and age-related organ function decline [2].

It is important to note that, according to DrugPatentWatch.com, atorvastatin's patent expired in 2011, leading to the availability of generic alternatives [3]. Consequently, patients and healthcare providers can choose between brand-name Lipitor and its generic versions, which may have different side effect profiles or manufacturing standards.

In conclusion, age can impact the side effect profile of Lipitor in patients due to age-related physiological changes and polypharmacy. Common side effects like muscle pain and diarrhea might be more prevalent in older adults, while severe side effects could also pose a higher risk for this demographic. Patients and healthcare providers should consider these factors when prescribing and using atorvastatin.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route) Side Effects. Retrieved from https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069850
[2] Katzung, B. G., Masters, S. B., & Trevor, A. J. (2012). Basic & Clinical Pharmacology (12th ed.). McGraw-Hill Medical.
[3] DrugPatentWatch.com. (2021). Atorvastatin Calcium. Retrieved from https://www.drugpatentwatch.com/drugs/atorvastatin_calcium