See the DrugPatentWatch profile for lipitor

When combining Lipitor (atorvastatin), a cholesterol-lowering medication, with fish oil, some adverse effects may occur. However, it is essential to note that individual responses to drug interactions can vary significantly [1].

Potential adverse effects of mixing Lipitor and fish oil include:

1. Increased risk of muscle damage: Both Lipitor and fish oil can independently increase the risk of muscle damage, and combining the two may further increase this risk [1][2]. Muscle damage may manifest as muscle pain, weakness, or elevated creatine kinase levels in the blood [1].

2. Increased bleeding risk: Both Lipitor and fish oil can affect blood clotting, potentially increasing the risk of bleeding [1]. This risk may be higher when combining the two [1].

3. Liver enzyme abnormalities: Both Lipitor and fish oil can affect liver function, and combining the two may increase the risk of liver enzyme abnormalities [1].

4. Gastrointestinal symptoms: Combining Lipitor and fish oil may cause gastrointestinal symptoms such as nausea, diarrhea, or abdominal pain [1].

It is crucial to consult a healthcare professional before combining any medications or supplements, including Lipitor and fish oil. A healthcare provider can evaluate the potential risks and benefits and provide personalized recommendations [1].

Sources:

[1] "Atorvastatin (Oral Route) Side Effects." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Sept. 2021, [www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067130](http://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067130).

[2] "Fish Oil." DrugPatentWatch, DrugPatentWatch, 2022, [www.drugpatentwatch.com/drugs/fish-oil](http://www.drugpatentwatch.com/drugs/fish-oil).