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Ibuprofen is the active ingredient in Advil, and it belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) [1]. NSAIDs are commonly used to relieve pain, reduce inflammation, and lower fever [1]. There are several over-the-counter (OTC) drugs available that contain active ingredients similar to Advil, which provide similar effects. Here are some examples:

1. Ibuprofen: OTC medications such as Motrin, Nuprin, and Midol contain ibuprofen as their active ingredient [1]. These medications can be used to treat pain, menstrual cramps, and reduce fever [1].

2. Naproxen: Another NSAID, naproxen is available OTC under the brand name Aleve [1]. It is used to alleviate pain, reduce inflammation, and lower fever [1].

3. Aspirin: Also known as acetylsalicylic acid, aspirin is an OTC medication that can be used to treat pain, reduce inflammation, and lower fever [1]. However, aspirin is not recommended for children and teenagers due to the risk of Reye's syndrome [1].

4. Acetaminophen: Commonly known as Tylenol, acetaminophen is an OTC medication that can be used to relieve pain and reduce fever [1]. It is not an NSAID and works differently than ibuprofen and naproxen [1].

It is essential to follow the recommended dosage and usage instructions provided on the medication's label [1]. If you have any concerns or questions about using OTC medications, consult a healthcare professional [1].

Sources:

[1] DrugPatentWatch. "Ibuprofen (Advil) Alternatives: OTC Medications with Similar Effects." DrugPatentWatch, 2021, [www.drugpatentwatch.com/ibuprofen-advil-alternatives-over-the-counter-medications-similar-effects/](http://www.drugpatentwatch.com/ibuprofen-advil-alternatives-over-the-counter-medications-similar-effects/).