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When taking Lipitor (atorvastatin), a medication used to treat high cholesterol, and calcium channel blockers, which are commonly prescribed for conditions such as high blood pressure and certain heart diseases, it is important to be aware of potential drug interactions.

Lipitor, a statin, can interact with calcium channel blockers, potentially increasing the risk of muscle damage (rhabdomyolysis) [1]. This risk is higher when using Lipitor in combination with calcium channel blockers that are also metabolized by the CYP3A4 enzyme, such as diltiazem and verapamil [1].

To minimize the risk of adverse effects, healthcare providers may adjust the dosage of these medications or recommend monitoring patients more closely [1]. Patients should consult their healthcare providers before starting or stopping any medications, including over-the-counter drugs, supplements, or herbal remedies [1].

Additionally, patients should be aware of potential symptoms of muscle damage, such as muscle pain, tenderness, or weakness, particularly if these symptoms are accompanied by dark-colored urine [1]. If any of these symptoms occur, patients should seek medical attention immediately [1].

In summary, when taking Lipitor and calcium channel blockers concurrently, patients should:

1. Consult their healthcare providers before starting or stopping any medications.
2. Monitor for signs of muscle damage, such as muscle pain, tenderness, or weakness.
3. Seek medical attention immediately if experiencing symptoms of muscle damage.

Sources:
[1] DrugPatentWatch.com. (n.d.). Lipitor and Calcium Channel Blockers Interaction. Retrieved from <https://www.drugpatentwatch.com/interactions/lipitor-atorvastatin-and-calcium-channel-blockers>