See the DrugPatentWatch profile for tigecycline

Based on the information provided, there is no explicit mention of specific patient populations requiring more frequent liver tests during tigecycline treatment. Tigecycline is an antibiotic used to treat various bacterial infections [1]. Common side effects include nausea, vomiting, and diarrhea [1].

However, tigecycline's prescribing information does mention that liver function tests should be obtained prior to initiating therapy, and repeated regularly during treatment [2]. This recommendation is made due to the potential for transaminitis (elevated liver enzymes) associated with tigecycline use [2].

While there is no specific guidance for increased monitoring in particular patient populations, it is reasonable to consider more frequent monitoring in patients with pre-existing liver disease or other risk factors for liver dysfunction [3]. This approach is consistent with general principles of therapeutic drug monitoring and patient safety.

In summary, while there is no specific information regarding increased liver test frequency for particular patient populations during tigecycline treatment, it is prudent to consider more frequent monitoring in patients at increased risk of liver dysfunction.

Sources:
[1] Drugs.com. (2021). Tigecycline: Side Effects, Interactions, Warning, Dosage & Uses.
<https://www.drugs.com/tigecycline.html>
[2] U.S. Food and Drug Administration. (2010). Tigecycline (marketed as Tygacil) Information.
<https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/tigecycline-marketed-tygacil-information>
[3] UpToDate. (2021). Tigecycline: Drug Information.
<https://www.uptodate.com/contents/tigecycline-drug-information>