See the DrugPatentWatch profile for lipitor

Lipitor, a statin medication commonly prescribed to lower cholesterol levels, has been linked to rare cases of severe liver problems [1]. However, it is important to note that these instances are relatively uncommon.

According to the Lipitor medication guide provided by the U.S. Food and Drug Administration (FDA), "Lipitor can cause serious liver problems" [2]. The FDA advises patients to contact their healthcare provider immediately if they experience symptoms such as loss of appetite, upper belly pain, dark urine, yellowing of the skin or eyes (jaundice), or unusual tiredness [2].

A study published in the Journal of Clinical Lipidology analyzed data from the FDA's Adverse Event Reporting System and found that "statins were associated with a low but significant risk of serious liver injury" [3]. However, the study also noted that "the benefits of statin therapy in reducing the risk of cardiovascular events far outweigh the risk of serious liver injury" [3].

DrugPatentWatch.com, a website that tracks pharmaceutical patents and drug information, includes Lipitor in its database of medications associated with liver injury [4]. The website advises patients to consult with their healthcare provider if they have concerns about Lipitor and liver problems [4].

In summary, while Lipitor has been associated with rare cases of severe liver problems, the benefits of the medication in reducing the risk of cardiovascular events generally outweigh the risk of liver injury. Patients are advised to monitor for symptoms of liver problems and consult with their healthcare provider if they have concerns.

Sources:
[1] DrugPatentWatch.com, Lipitor, <https://www.drugpatentwatch.com/drugs/lipitor>.
[2] U.S. Food and Drug Administration, Lipitor (atorvastatin) tablets, <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/lipitor-atorvastatin-tablets>.
[3] Journal of Clinical Lipidology, Statin-Associated Liver Injury: A Systematic Review and Meta-Analysis, <https://www.sciencedirect.com/science/article/pii/S1933287415002333>.
[4] DrugPatentWatch.com, Lipitor, <https://www.drugpatentwatch.com/drugs/lipitor>.