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Yes, there are specific safety guidelines for the use of Lipitor, a statin medication used to treat high cholesterol, and calcium channel blockers, a type of medication used to treat hypertension and certain heart conditions.

Lipitor (atorvastatin) has the following safety guidelines:

1. It should not be taken by individuals with active liver disease or unexplained elevations in liver function tests [1].
2. Caution should be exercised when Lipitor is administered to patients with a history of liver disease or heavy alcohol consumption [1].
3. Lipitor should be used with caution in patients with a history of seizures or electrolyte imbalances [1].
4. Grapefruit and grapefruit juice should be avoided while taking Lipitor as it can increase the concentration of atorvastatin in the blood and lead to adverse effects [1].

Calcium channel blockers have the following safety guidelines:

1. Calcium channel blockers should be used with caution in patients with impaired hepatic or renal function [2].
2. Calcium channel blockers should be used with caution in patients with a history of heart failure or low blood pressure [2].
3. Calcium channel blockers can interact with other medications, such as beta blockers, leading to a dangerous drop in blood pressure [2].
4. Grapefruit and grapefruit juice should be avoided while taking certain calcium channel blockers, such as verapamil and nifedipine, as it can increase the concentration of the medication in the blood and lead to adverse effects [2].

It is important to note that these safety guidelines may vary depending on the specific calcium channel blocker being used. It is always best to consult with a healthcare provider for specific safety information regarding a particular medication.

Sources:
[1] "Lipitor-atorvastatin Calcium Tablets," Drugs.com, <https://www.drugs.com/lipitor.html>.
[2] "Calcium Channel Blockers," Mayo Clinic, <https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/calcium-channel-blockers/art-20047651>.
[3] "Lipitor (Atorvastatin Calcium) Drug Interactions," DrugPatentWatch.com, <https://www.drugpatentwatch.com/drugs/lipitor/interactions>.
[4] "Calcium Channel Blockers," RxList, <https://www.rxlist.com/calcium_channel_blockers/drugs-condition.htm>.