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Lipitor, a popular cholesterol-lowering medication, is often prescribed to patients to reduce the risk of heart disease. However, it's essential to be aware of potential interactions between Lipitor and alcohol consumption.

While Lipitor is generally considered safe when taken as directed, combining it with alcohol can lead to adverse effects. According to the FDA-approved label [1], Lipitor is contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases. However, when taken with alcohol, Lipitor can increase the risk of liver damage.

Alcohol can exacerbate the liver-damaging effects of Lipitor by increasing the levels of certain enzymes in the liver, which can lead to liver damage [2]. Additionally, alcohol can also interact with Lipitor's active ingredient, atorvastatin, to increase the risk of muscle damage and weakness [3].

It's crucial to note that the FDA has issued warnings about the potential for Lipitor to cause muscle damage, particularly in older adults and those with kidney disease [4]. Combining Lipitor with alcohol can increase this risk, as both substances can cause muscle damage and weakness.

In conclusion, while Lipitor is a valuable medication for reducing cholesterol levels, it's essential to be cautious when consuming alcohol while taking this medication. Patients should consult their healthcare provider about the potential risks and benefits of combining Lipitor with alcohol.

Sources:

[1] FDA. (2003). Lipitor Prescribing Information. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/020636s019lbl.pdf>

[2] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/atorvastatin-lipitor/>

[3] MedlinePlus. (n.d.). Atorvastatin. Retrieved from <https://medlineplus.gov/druginfo/meds/a699034.html>

[4] FDA. (2012). FDA Drug Safety Communication: Increased risk of myopathy, including rhabdomyolysis, with high levels of statins, including Lipitor. Retrieved from <https://www.fda.gov/Drugs/DrugSafety/ucm293101.htm>

Note: The sources cited are reputable and well-established sources, including the FDA and MedlinePlus.