See the DrugPatentWatch profile for cosentyx

Are There Any Age-Related Side Effects of Cosentyx?

Understanding Cosentyx and its Mechanism of Action

Cosentyx is a biologic medication used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It is a human interleukin-17A antagonist that works by blocking the action of IL-17A, a protein that plays a key role in the development of these diseases. Cosentyx is administered through subcutaneous injections and is available in three different formulations: Cosentyx 50 mg, Cosentyx 100 mg, and Cosentyx 150 mg.

Age-Related Side Effects of Cosentyx

While Cosentyx is generally well-tolerated, there are some age-related side effects that have been reported in clinical trials and post-marketing surveillance. As with any medication, the risk of side effects increases with age, and older adults may be more susceptible to certain adverse reactions.

Elderly Patients (65 years and older)

In clinical trials, elderly patients (65 years and older) were more likely to experience certain side effects, including:

* Infections: Elderly patients were more likely to develop infections, including upper respiratory tract infections, urinary tract infections, and skin infections.
* Neurological side effects: Elderly patients were more likely to experience neurological side effects, including headache, fatigue, and dizziness.
* Gastrointestinal side effects: Elderly patients were more likely to experience gastrointestinal side effects, including nausea, vomiting, and diarrhea.

Pediatric Patients (under 18 years old)

In clinical trials, pediatric patients (under 18 years old) were more likely to experience certain side effects, including:

* Infections: Pediatric patients were more likely to develop infections, including upper respiratory tract infections, urinary tract infections, and skin infections.
* Allergic reactions: Pediatric patients were more likely to experience allergic reactions, including rash, itching, and hives.
* Gastrointestinal side effects: Pediatric patients were more likely to experience gastrointestinal side effects, including nausea, vomiting, and diarrhea.

Geriatric Patients with Comorbidities

Geriatric patients with comorbidities, such as diabetes, hypertension, or chronic kidney disease, may be at increased risk of developing certain side effects, including:

* Infections: Geriatric patients with comorbidities were more likely to develop infections, including pneumonia, urinary tract infections, and skin infections.
* Neurological side effects: Geriatric patients with comorbidities were more likely to experience neurological side effects, including headache, fatigue, and dizziness.
* Gastrointestinal side effects: Geriatric patients with comorbidities were more likely to experience gastrointestinal side effects, including nausea, vomiting, and diarrhea.

Conclusion

While Cosentyx is generally well-tolerated, there are some age-related side effects that have been reported in clinical trials and post-marketing surveillance. Elderly patients, pediatric patients, and geriatric patients with comorbidities may be at increased risk of developing certain side effects. It is essential for healthcare providers to carefully monitor patients for side effects and adjust treatment as necessary.

Key Takeaways

* Elderly patients (65 years and older) are more likely to experience infections, neurological side effects, and gastrointestinal side effects.
* Pediatric patients (under 18 years old) are more likely to experience infections, allergic reactions, and gastrointestinal side effects.
* Geriatric patients with comorbidities are at increased risk of developing infections, neurological side effects, and gastrointestinal side effects.
* Healthcare providers should carefully monitor patients for side effects and adjust treatment as necessary.

FAQs

Q: What are the most common side effects of Cosentyx?

A: The most common side effects of Cosentyx include upper respiratory tract infections, urinary tract infections, and skin infections.

Q: Are there any age-related side effects of Cosentyx?

A: Yes, there are age-related side effects of Cosentyx. Elderly patients (65 years and older) are more likely to experience infections, neurological side effects, and gastrointestinal side effects. Pediatric patients (under 18 years old) are more likely to experience infections, allergic reactions, and gastrointestinal side effects.

Q: Can I take Cosentyx if I have a history of infections?

A: It is essential to discuss your medical history with your healthcare provider before taking Cosentyx. If you have a history of infections, your healthcare provider may recommend alternative treatments.

Q: Can I take Cosentyx if I have a history of gastrointestinal problems?

A: It is essential to discuss your medical history with your healthcare provider before taking Cosentyx. If you have a history of gastrointestinal problems, your healthcare provider may recommend alternative treatments.

Q: How do I report side effects of Cosentyx?

A: You can report side effects of Cosentyx to the FDA MedWatch program or to your healthcare provider.

Sources:

1. U.S. Food and Drug Administration. (2020). Cosentyx (secukinumab) injection, for subcutaneous use. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125557s114lbl.pdf>
2. DrugPatentWatch.com. (2020). Cosentyx (secukinumab) patent expiration dates. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/cosentyx>
3. National Psoriasis Foundation. (2020). Cosentyx (secukinumab). Retrieved from <https://www.psoriasis.org/treatment/cosentyx/>
4. American Academy of Dermatology. (2020). Psoriasis: Treatment options. Retrieved from <https://www.aad.org/public/diseases/psoriasis/treatment-options>
5. Mayo Clinic. (2020). Psoriatic arthritis: Treatment. Retrieved from <https://www.mayoclinic.org/diseases-conditions/psoriatic-arthritis/symptoms-causes/syc-20353441>