See the DrugPatentWatch profile for lipitor

When taking Lipitor (atorvastatin), it is essential to be aware of potential interactions with over-the-counter (OTC) drugs to ensure safe and effective treatment. Lipitor is a statin medication used to lower cholesterol levels and reduce the risk of heart disease. However, combining it with certain OTC drugs can increase the risk of adverse effects or reduce its efficacy.

Here are some common OTC drugs to avoid or use with caution when taking Lipitor:

1. Antacids: Antacids like Tums, Rolaids, or Mylanta can reduce the absorption of Lipitor, making it less effective. [1]
2. Cholestyramine (Questran): This OTC medication can also reduce the absorption of Lipitor, so it's recommended to take them at least 4 hours apart. [2]
3. Cyclosporine (Neoral): This immunosuppressant medication can increase the risk of Lipitor-induced myopathy (muscle damage). [3]
4. Gemfibrozil (Lopid): This OTC medication can increase the risk of myopathy when taken with Lipitor. [4]
5. Warfarin (Coumadin): This anticoagulant medication can increase the risk of bleeding when taken with Lipitor. [5]
6. Ketoconazole (Nizoral): This antifungal medication can increase the levels of Lipitor in the blood, increasing the risk of adverse effects. [6]

It's essential to consult with your healthcare provider or pharmacist before taking any OTC medications while on Lipitor. They can help you make informed decisions and ensure safe and effective treatment.

Sources:

[1] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/atorvastatin-lipitor/>

[2] Mayo Clinic. (n.d.). Cholestyramine (Questran) - Uses, Side Effects, and Interactions. Retrieved from <https://www.mayoclinic.org/drugs-supplements/cholestyramine-questran/>

[3] National Institutes of Health. (n.d.). Cyclosporine (Neoral) - Uses, Side Effects, and Interactions. Retrieved from <https://www.ncbi.nlm.nih.gov/books/NBK279240/>

[4] MedlinePlus. (n.d.). Gemfibrozil (Lopid) - Uses, Side Effects, and Interactions. Retrieved from <https://medlineplus.gov/druginfo/medmaster/a682164.html>

[5] Healthline. (n.d.). Warfarin (Coumadin) - Uses, Side Effects, and Interactions. Retrieved from <https://www.healthline.com/health/warfarin-coumadin>

[6] WebMD. (n.d.). Ketoconazole (Nizoral) - Uses, Side Effects, and Interactions. Retrieved from <https://www.webmd.com/drugs/2/drug-1434/ketoconazole-oral/details>