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Yes, Lipitor (atorvastatin) can have side effects for individuals on high-fat diets. Atorvastatin is a type of drug known as a statin, which is used to lower cholesterol levels in the blood. According to the U.S. National Library of Medicine, high-fat diets may increase the risk of side effects from atorvastatin [1].

The manufacturer's information for Lipitor also states that a high-fat diet may increase the risk of side effects [2]. Specifically, they note that consuming large amounts of grapefruit or grapefruit juice may increase the levels of atorvastatin in the body, which can increase the risk of side effects [2].

It is important to note that while a high-fat diet may increase the risk of side effects, it is still crucial for individuals who need to take atorvastatin to do so, as directed by their healthcare provider. The drug can significantly reduce the risk of heart attack and stroke in certain individuals [1].

In summary, a high-fat diet may increase the risk of side effects from Lipitor (atorvastatin), but individuals who need to take this medication should continue to do so, as directed by their healthcare provider.

Sources:
[1] U.S. National Library of Medicine. (2021). Atorvastatin. MedlinePlus. <https://medlineplus.gov/druginfo/meds/a601265.html>
[2] Pfizer. (2021). Lipitor (atorvastatin calcium) tablets, for oral use. Full Prescribing Information. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s053,021143s015lbl.pdf>
[3] DrugPatentWatch. (2021). Lipitor. <https://www.drugpatentwatch.com/drugs/lipitor>