See the DrugPatentWatch profile for aspirin

Aspirin and new drugs for headaches function differently in terms of their mechanisms. Aspirin, also known as acetylsalicylic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are hormone-like substances that cause inflammation and trigger pain signals in the brain [1][2]. Aspirin's mechanism of action also includes the inhibition of blood clotting, which makes it useful in preventing heart attacks and strokes [1].

On the other hand, new drugs for headaches have different mechanisms of action. For instance, some new drugs work by targeting and blocking the activity of calcitonin gene-related peptide (CGRP), a molecule that plays a crucial role in migraine attacks [3]. These drugs, known as CGRP antagonists or gepants, have shown promising results in clinical trials and have been approved by the FDA for the treatment of migraines [3].

In summary, aspirin and new drugs for headaches have different mechanisms of action. Aspirin works by inhibiting the production of prostaglandins and the clotting of blood, while new drugs such as CGRP antagonists target and block the activity of CGRP, a molecule involved in migraine attacks.

Sources:

[1] <https://www.drugpatentwatch.com/p/tradename/ASPIRIN>

[2] <https://www.ncbi.nlm.nih.gov/books/NBK547742/>

[3] <https://www.yalemedicine.org/news/acetaminophen-nsaids-over-the-counter-pain-relievers>