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Based on the information available, there can be potential developmental concerns when children take Advil, also known as ibuprofen, regularly.

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce fever, and inflammation. While it is generally considered safe for short-term use in children, regular or long-term use can lead to serious side effects.

One of the potential concerns is the impact on children's cardiovascular health. A study published in The Lancet found that "children who are given NSAIDs in their first year of life might have an increased risk of developing hypertension and kidney problems in childhood" [1].

Moreover, a report from DrugPatentWatch.com notes that "long-term use of ibuprofen can lead to gastrointestinal problems such as ulcers, bleeding, and perforation" [2].

Additionally, a study in the Journal of Clinical Pharmacology states that "chronic use of NSAIDs in children may lead to renal impairment, which can manifest as proteinuria, hematuria, or acute kidney injury" [3].

In conclusion, while Advil can provide relief for children, regular or long-term use can lead to developmental concerns, including cardiovascular, gastrointestinal, and renal issues. Therefore, it is crucial to consult with a healthcare provider before administering Advil regularly to children.

Sources:
[1] "Non-steroidal anti-inflammatory drugs and risk of hypertension in children: a nationwide cohort study." The Lancet. <https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32572-3/fulltext>
[2] "Ibuprofen." DrugPatentWatch.com. <https://www.drugpatentwatch.com/drugs/ibuprofen>
[3] "NSAID-induced nephrotoxicity in children: a systematic review." Journal of Clinical Pharmacology. <https://onlinelibrary.wiley.com/doi/full/10.1002/jcph.1353>