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When taking Lipitor (atorvastatin), a cholesterol-lowering medication, it is important to be cautious about potential interactions with other medications, including pain medications. According to sources [2] and [3], it is generally safe to take acetaminophen (Tylenol) with Lipitor. Acetaminophen is a common over-the-counter pain reliever that is often recommended for individuals taking statins like Lipitor. However, it is crucial to consult with a healthcare provider or pharmacist before combining any medications to ensure there are no contraindications or adverse effects.

Sources:
[2] https://www.goodrx.com/atorvastatin/interactions
[3] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/