See the DrugPatentWatch profile for lipitor
Lipitor, also known as atorvastatin, is a medication used to decrease the risk of heart disease. It belongs to a class of drugs called statins, which work by blocking a substance your body needs to make cholesterol [1].
The mechanism by which Lipitor decreases heart disease risk involves lowering the levels of low-density lipoprotein (LDL), or "bad" cholesterol, and triglycerides in the blood, while increasing the levels of high-density lipoprotein (HDL), or "good" cholesterol [1]. High levels of LDL and triglycerides, and low levels of HDL can lead to a buildup of plaque in the arteries, which can cause heart disease and stroke [1].
Lipitor inhibits the enzyme HMG-CoA reductase, which is necessary for the production of cholesterol in the body [1]. By inhibiting this enzyme, Lipitor reduces the amount of cholesterol that can be made and, in turn, reduces the amount of cholesterol that can be deposited in the arteries [1].
Additionally, Lipitor has been shown to have anti-inflammatory and antioxidant properties, which may contribute to its ability to reduce the risk of heart disease [2].
It is important to note that Lipitor is not a cure for heart disease and should be used in conjunction with a heart-healthy lifestyle, including a healthy diet, regular exercise, and smoking cessation [1].
In summary, Lipitor decreases the risk of heart disease by lowering LDL and triglycerides, increasing HDL, inhibiting the production of cholesterol, and having anti-inflammatory and antioxidant properties.
Sources:
[1] "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 1 Jan. 2022, medlineplus.gov/druginfo/meds/a601249.html.
[2] "Atorvastatin." DrugPatentWatch, drugpatentwatch.com/drug/atorvastatin.