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When considering taking Advil (ibuprofen) and Tylenol (acetaminophen) together, it is essential to understand the potential interactions and risks involved. Both medications are common over-the-counter pain relievers and fever reducers, but combining them may not always be safe.

Potential risks of combining Advil and Tylenol include:

1. **Overdose**: Both Advil and Tylenol have maximum daily dosage limits. Exceeding these limits by taking both medications together can lead to overdose, which may cause liver damage or other serious health complications [1].

2. **Gastrointestinal issues**: Ibuprofen, the active ingredient in Advil, can increase the risk of gastrointestinal side effects, such as stomach ulcers, bleeding, and perforations. Concurrent use with Tylenol may exacerbate these risks [1].

3. **Kidney damage**: Ibuprofen can also affect kidney function, and long-term or excessive use may increase the risk of kidney damage or failure. Combining it with Tylenol may further increase this risk [1].

4. **Interactions with other medications**: Both Advil and Tylenol can interact with other medications, potentially leading to adverse effects. Combining the two may increase the likelihood and severity of these interactions [1].

Before taking Advil and Tylenol together, consult a healthcare professional or pharmacist to assess the potential risks and determine the safest course of action. Always follow the recommended dosages and instructions for each medication.

Sources:

1. DrugPatentWatch. "Advil (ibuprofen) and Tylenol (acetaminophen) Drug Interactions." Accessed April 25, 2023. <https://www.drugpatentwatch.com/drug-interactions/advil-ibuprofen-tylenol-acetaminophen>.