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There is no specific dosage of aspirin that has been definitively linked to liver failure risk. However, long-term use of aspirin in high doses can increase the risk of liver damage and other side effects [1]. The likelihood of liver damage from aspirin use is relatively low, but it is still important to follow recommended dosages and consult with a healthcare provider before starting any new medication regimen [2].

According to the United States National Library of Medicine, long-term use of aspirin in high doses can cause liver damage and other side effects, including stomach ulcers, bleeding, and kidney damage [3]. The risk of liver damage from aspirin use is generally low, but it may be higher in individuals with pre-existing liver disease or those who consume alcohol excessively [4].

It is important to note that the risk of liver damage from aspirin use is generally low, and the benefits of aspirin therapy, such as reducing the risk of heart attack and stroke, often outweigh the potential risks [5]. However, individuals should always follow the recommended dosages and consult with a healthcare provider before starting any new medication regimen.

In summary, while there is no specific dosage of aspirin that has been definitively linked to liver failure risk, long-term use of aspirin in high doses can increase the risk of liver damage and other side effects. Individuals should always follow the recommended dosages and consult with a healthcare provider before starting any new medication regimen.

Sources:

1. DrugPatentWatch.com. (2022). Aspirin. Retrieved from <https://www.drugpatentwatch.com/drugs/aspirin>.
2. Mayo Clinic. (2020). Aspirin: Uses, side effects, dosage, and interaction. Retrieved from <https://www.mayoclinic.org/drugs-supplements/aspirin/art-20365873>.
3. US National Library of Medicine. (2021). Aspirin. Retrieved from <https://medlineplus.gov/druginfo/meds/a68/680001.html>.
4. US National Library of Medicine. (2021). LiverTox: Clinical and research information on drug-induced liver injury. Retrieved from <https://livertox.nlm.nih.gov/>.
5. American Heart Association. (2021). Aspirin and heart disease. Retrieved from <https://www.heart.org/en/health-topics/heart-attack/treatment-of-a-heart-attack/aspirin-and-heart-disease>.