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Should lipitor be discontinued if liver enzymes elevate?

See the DrugPatentWatch profile for lipitor

The decision to discontinue Lipitor (atorvastatin) if liver enzymes elevate depends on the severity of the elevation and the patient's overall health. Lipitor is a statin medication used to lower cholesterol levels and reduce the risk of heart disease.

According to the FDA-approved labeling for Lipitor, liver enzymes may increase in some patients taking the medication. However, this does not necessarily mean that the medication should be discontinued. [1]

The FDA recommends that liver enzyme levels be monitored regularly in patients taking Lipitor, particularly in those with pre-existing liver disease or those taking other medications that may affect liver function. If liver enzymes increase, the patient's healthcare provider may need to adjust the dosage or discontinue the medication. [2]

The decision to discontinue Lipitor should be based on the severity of the liver enzyme elevation and the patient's overall health. Mild elevations in liver enzymes may not require discontinuation of the medication, while more significant elevations may warrant discontinuation. [3]

It's also important to note that Lipitor is not the only statin medication available. Patients who experience liver enzyme elevations while taking Lipitor may be able to switch to a different statin medication. [4]

In conclusion, the decision to discontinue Lipitor if liver enzymes elevate should be made on a case-by-case basis, taking into account the severity of the elevation and the patient's overall health.

Sources:

1. Pfizer. (2003). Lipitor Prescribing Information. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/020992lbl.pdf>
2. FDA. (2011). Lipitor (atorvastatin calcium) Tablets. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020992s021lbl.pdf>
3. DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/calcium-channel-blockers/atorvastatin-lipitor-patent-expiration>
4. Mayo Clinic. (n.d.). Statins: What are the differences between statins? Retrieved from <https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/statins/faq-20058055>

Note: The information provided is based on publicly available data and should not be considered as medical advice. Patients should consult their healthcare provider for personalized guidance on the use of Lipitor and other medications.


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