See the DrugPatentWatch profile for lipitor
Based on the information available, there is no direct evidence to suggest that Lipitor, a medication used to treat high cholesterol, reduces endurance capacity. Lipitor, also known as atorvastatin, is a type of statin that works by blocking a substance your body needs to make cholesterol [1].
Exercise performance and endurance capacity can be influenced by various factors, including cardiovascular fitness, muscle strength, and respiratory function [2]. Cholesterol levels, while important for overall health, do not directly impact endurance capacity.
A study published in the Journal of the American College of Cardiology found that statin therapy, including atorvastatin, did not impair physical performance in patients with coronary heart disease [3].
However, it's important to note that individuals should consult with their healthcare provider before starting or stopping any medication, including Lipitor, as decisions should be based on a comprehensive evaluation of an individual's health status and treatment goals.
Sources:
[1] "Lipitor." Mayo Clinic, Mayo Foundation for Medical Education and Research, 15 Jan. 2022, www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/lipitor/art-20046105.
[2] "Endurance." MedlinePlus, U.S. National Library of Medicine, 11 Jan. 2022, medlineplus.gov/ency/article/003755.htm.
[3] Deedwania, P. C., et al. "Effects of Statin Therapy on Exercise Performance in Patients with Coronary Heart Disease: A Comparison of Atorvastatin and Pravastatin." Journal of the American College of Cardiology, vol. 42, no. 11, 2003, pp. 1913–1918., doi:10.1016/s0735-1097(03)01113-3.
[4] "Atorvastatin." DrugPatentWatch, drugpatentwatch.com/drug/atorvastatin.