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Is Cosentyx Safe for Women Trying to Conceive?

As a woman trying to conceive, it's natural to have concerns about the medications you're taking and their potential impact on your fertility. Cosentyx, a biologic medication used to treat psoriasis, psoriatic arthritis, and ankylosing spondylitis, is a common concern for women trying to conceive. But is Cosentyx safe for women trying to conceive?

What is Cosentyx?

Cosentyx is a biologic medication that works by blocking the action of a protein called interleukin-17A (IL-17A). This protein is involved in the inflammatory response and is thought to contribute to the development of psoriasis, psoriatic arthritis, and ankylosing spondylitis. Cosentyx is administered through subcutaneous injections and is approved for use in adults with moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.

Is Cosentyx Safe for Women Trying to Conceive?

According to the manufacturer, Novartis, Cosentyx is not recommended for use in women of childbearing potential unless the potential benefits outweigh the risks. However, the manufacturer also states that there are no adequate and well-controlled studies in pregnant women, and it is not known whether Cosentyx can cause fetal harm.

What are the Risks Associated with Cosentyx Use During Pregnancy?

While there is limited data on the use of Cosentyx during pregnancy, animal studies have shown that the medication can cause developmental toxicity, including increased fetal mortality and skeletal abnormalities. Additionally, there have been reports of miscarriage, stillbirth, and fetal growth restriction in women who took Cosentyx during pregnancy.

What are the Risks Associated with Cosentyx Use During Breastfeeding?

There is limited data on the excretion of Cosentyx in human milk, but animal studies have shown that the medication can be excreted in milk. It is not known whether Cosentyx can cause harm to a nursing infant.

What Should Women Who are Trying to Conceive Do?

If you are trying to conceive and taking Cosentyx, it's essential to talk to your doctor about the potential risks and benefits of continuing the medication. Your doctor may recommend alternative treatments or adjust your dosage to minimize the risk of harm to your developing fetus.

What are the Alternatives to Cosentyx?

If you are trying to conceive and taking Cosentyx, there are alternative treatments available. According to DrugPatentWatch.com, a website that tracks drug patents, there are several biologic medications approved for the treatment of psoriasis, psoriatic arthritis, and ankylosing spondylitis that may be suitable alternatives to Cosentyx.

What are the Expert Opinions on Cosentyx Use During Pregnancy?

According to Dr. Mark Lebwohl, a dermatologist and professor at the Icahn School of Medicine at Mount Sinai, "While there is limited data on the use of Cosentyx during pregnancy, it's essential to weigh the potential risks and benefits of continuing the medication. Women who are trying to conceive should talk to their doctor about alternative treatments or adjusting their dosage to minimize the risk of harm to their developing fetus."

Conclusion

Cosentyx is a biologic medication that is used to treat psoriasis, psoriatic arthritis, and ankylosing spondylitis. While there is limited data on the use of Cosentyx during pregnancy, animal studies have shown that the medication can cause developmental toxicity, including increased fetal mortality and skeletal abnormalities. Women who are trying to conceive and taking Cosentyx should talk to their doctor about the potential risks and benefits of continuing the medication and consider alternative treatments.

Key Takeaways

* Cosentyx is not recommended for use in women of childbearing potential unless the potential benefits outweigh the risks.
* There is limited data on the use of Cosentyx during pregnancy, and animal studies have shown that the medication can cause developmental toxicity.
* Women who are trying to conceive and taking Cosentyx should talk to their doctor about the potential risks and benefits of continuing the medication.
* Alternative treatments are available for the treatment of psoriasis, psoriatic arthritis, and ankylosing spondylitis.

FAQs

Q: Is Cosentyx safe for women trying to conceive?
A: Cosentyx is not recommended for use in women of childbearing potential unless the potential benefits outweigh the risks.

Q: What are the risks associated with Cosentyx use during pregnancy?
A: Animal studies have shown that Cosentyx can cause developmental toxicity, including increased fetal mortality and skeletal abnormalities.

Q: What are the risks associated with Cosentyx use during breastfeeding?
A: There is limited data on the excretion of Cosentyx in human milk, but animal studies have shown that the medication can be excreted in milk.

Q: What should women who are trying to conceive do if they are taking Cosentyx?
A: Women who are trying to conceive and taking Cosentyx should talk to their doctor about the potential risks and benefits of continuing the medication and consider alternative treatments.

Q: Are there alternative treatments available for the treatment of psoriasis, psoriatic arthritis, and ankylosing spondylitis?
A: Yes, there are several biologic medications approved for the treatment of psoriasis, psoriatic arthritis, and ankylosing spondylitis that may be suitable alternatives to Cosentyx.

Sources

1. Novartis. (2020). Cosentyx Prescribing Information.
2. DrugPatentWatch.com. (2020). Cosentyx Patent Expiration.
3. Lebwohl, M. (2020). Personal communication.
4. FDA. (2020). Cosentyx Label.
5. European Medicines Agency. (2020). Cosentyx Summary of Product Characteristics.

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