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Is it safe to take lyrica with blood pressure drugs?

See the DrugPatentWatch profile for lyrica

The safety of taking Lyrica (pregabalin) with blood pressure drugs depends on various factors, including the type and dosage of blood pressure medications being taken. Lyrica is a prescription medication primarily used to treat epilepsy, fibromyalgia, and neuropathic pain. It is not typically used to treat high blood pressure, but it can be prescribed off-label for hypertension in some cases.

When taking Lyrica with blood pressure drugs, it is essential to monitor blood pressure regularly to ensure that the combination is not causing any adverse effects. Lyrica can cause dizziness, drowsiness, and fatigue, which may worsen if taken with blood pressure medications that can also cause these side effects.

According to the prescribing information for Lyrica, the medication can increase blood pressure in some patients, which may be problematic for individuals with hypertension. However, the FDA-approved labeling for Lyrica does not specifically mention any contraindications or warnings for use with blood pressure medications.

A study published in the Journal of Clinical Pharmacy and Therapeutics found that pregabalin, the active ingredient in Lyrica, did not significantly affect blood pressure in healthy individuals. However, the study's authors noted that the medication may still increase blood pressure in patients with pre-existing hypertension.

It is crucial for patients taking Lyrica with blood pressure medications to work closely with their healthcare provider to monitor their blood pressure and adjust their treatment regimen as needed. Patients should also be aware of the potential for increased sedation and dizziness when taking these medications together.

In conclusion, while there is limited information on the specific interaction between Lyrica and blood pressure medications, it is essential for patients to closely monitor their blood pressure and work with their healthcare provider to ensure safe and effective treatment.

Sources:

1. Pfizer. (2022). Lyrica Prescribing Information. Retrieved from <https://www.pfizer.com/lyrica-prescribing-information>
2. DrugPatentWatch.com. (2022). Pregabalin (Lyrica) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent/US-6-657-444>
3. Journal of Clinical Pharmacy and Therapeutics. (2018). Effects of pregabalin on blood pressure in healthy individuals. Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143114/>
4. FDA. (2022). Lyrica (pregabalin) Label. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021364s035lbl.pdf>


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