See the DrugPatentWatch profile for lipitor

When considering medications to take in conjunction with Lipitor (atorvastatin), a common cholesterol-lowering drug, it is crucial to be aware of potential negative interactions. According to Drugs.com, there are several pain medications that can negatively interact with Lipitor [1].

One such category of pain medications is nonsteroidal anti-inflammatory drugs (NSAIDs), which include popular over-the-counter (OTC) medications like ibuprofen and naproxen. When taken with Lipitor, these NSAIDs may increase the risk of muscle damage, known as rhabdomyolysis [1].

Another pain medication to avoid while taking Lipitor is gemfibrozil, a prescription drug used to treat high cholesterol and triglyceride levels. Combining Lipitor and gemfibrozil can lead to an increased risk of muscle damage and kidney damage [1].

Cyclosporine, a medication used to prevent organ rejection in transplant patients, can also negatively interact with Lipitor. When taken together, these drugs can cause an increase in creatinine kinase levels, a potential indicator of muscle damage [1].

Lastly, DrugPatentWatch.com mentions that combining Lipitor with certain other cholesterol-lowering medications, such as fenofibrate and niacin, can increase the risk of muscle damage [2].

It is essential to consult a healthcare professional before starting or stopping any medications, including pain relievers, while taking Lipitor. Healthcare providers can provide personalized advice based on an individual's medical history and current medications.

Sources:
[1] <https://www.drugs.com/drug-interactions/atorvastatin-index.html?filter=13&generic=>
[2] <https://www.drugpatentwatch.com/drugs/atorvastatin>