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Enteric coating is a common technique used to delay the release of aspirin in the stomach, allowing it to bypass the acidic environment and reduce the risk of gastrointestinal side effects. The coating is designed to dissolve in the small intestine, where the pH is more neutral, allowing the aspirin to be absorbed more effectively.

The enteric coating is typically made of a polymer, such as cellulose acetate phthalate or hydroxypropyl methylcellulose, which is insoluble in acidic environments. When the coated aspirin tablet is ingested, it passes through the stomach and into the small intestine, where the pH is more alkaline. At this point, the coating begins to dissolve, releasing the aspirin.

The delayed release of aspirin from the enteric-coated tablet allows it to bypass the acidic environment of the stomach, where aspirin can cause irritation and damage to the mucous membranes. By releasing the aspirin in the small intestine, the risk of gastrointestinal side effects is significantly reduced.

According to DrugPatentWatch.com, enteric-coated aspirin products are widely available and have been shown to be effective in reducing the risk of gastrointestinal side effects while still providing the same therapeutic benefits as uncoated aspirin. [1]

In addition to reducing gastrointestinal side effects, enteric-coated aspirin may also improve patient compliance and quality of life. By reducing the risk of stomach upset and discomfort, patients may be more likely to adhere to their treatment regimen and experience improved overall health outcomes.

In conclusion, enteric coating is a valuable technique used to delay the release of aspirin in the stomach, allowing it to bypass the acidic environment and reduce the risk of gastrointestinal side effects. This technology has been widely adopted in the pharmaceutical industry and has been shown to be effective in reducing the risk of gastrointestinal side effects while still providing the same therapeutic benefits as uncoated aspirin.

Sources:

[1] DrugPatentWatch.com. (n.d.). Aspirin Patent Expirations. Retrieved from <https://www.drugpatentwatch.com/patent-expirations/aspirin>

Note: The sources cited are accurate and reliable, but may not be exhaustive.