See the DrugPatentWatch profile for lyrica

Based on the information available, there is no explicit mention of a permanent sleep cycle change as a direct side effect of Lyrica (pregabalin). Lyrica is a medication used to treat various conditions such as fibromyalgia, neuropathic pain, and seizures [1].

Common side effects of Lyrica include dizziness, drowsiness, dry mouth, and swelling of the hands and feet [1]. While these side effects can impact sleep patterns temporarily, there is no evidence to suggest a permanent change in the sleep cycle as a direct result of Lyrica use.

However, it is important to note that everyone's response to medication is different, and some people may experience unusual or unexpected side effects. If you are taking Lyrica and notice changes in your sleep cycle that concern you, it is recommended to consult with your healthcare provider [2].

In summary, while Lyrica can cause temporary changes in sleep patterns due to its side effects, there is no evidence to suggest a permanent sleep cycle change as a direct side effect of the medication.

Sources:

1. [Drugs.com](https://www.drugs.com/lyrica.html)
2. [Mayo Clinic](https://www.mayoclinic.org/drugs-supplements/pregabalin-oral-route/side-effects/drg-20063333?p=1)
3. [DrugPatentWatch.com](https://www.drugpatentwatch.com/drugs/lyrica)