See the DrugPatentWatch profile for ativan
Yes, there are risks associated with increasing the dosage of Ativan (lorazepam) for severe epilepsy. Ativan is a benzodiazepine medication commonly used to treat anxiety disorders, but it can also be used to manage seizures in certain cases of epilepsy [1].
Increasing the dosage of Ativan for epilepsy should be done under the close supervision of a healthcare professional, as there are potential risks and side effects associated with its use. According to the National Library of Medicine, common side effects of Ativan include drowsiness, dizziness, and weakness [2]. More serious side effects can include mental/mood changes (such as hallucinations, depression, thoughts of suicide), trouble speaking, vision changes, or loss of coordination [2].
Moreover, long-term use of benzodiazepines like Ativan can lead to dependence and tolerance, meaning that higher doses may be required to achieve the same effect over time [3]. This can increase the risk of side effects and withdrawal symptoms if the medication is stopped suddenly.
It is important to note that while increasing the dosage of Ativan may help control seizures in some cases of severe epilepsy, it may not be effective for all types of epilepsy [4]. Other treatment options, such as surgery or alternative medications, may be more appropriate in certain cases.
In summary, while increasing the dosage of Ativan may be necessary to manage severe epilepsy, it is important to be aware of the potential risks and side effects associated with its use. Close monitoring by a healthcare professional is essential, and other treatment options should be considered if necessary.
Sources:
[1] DrugPatentWatch.com. (n.d.). Ativan (Lorazepam) Patent Expiration & Drug Patents. Retrieved from <
https://www.drugpatentwatch.com/drugs/ativan>
[2] MedlinePlus. (2021, March 1). Lorazepam. Retrieved from <
https://medlineplus.gov/druginfo/meds/a682035.html>
[3] National Institute on Drug Abuse. (2020, June 1). Benzodiazepines and Opioids. Retrieved from <
https://www.drugabuse.gov/drug-topics/opioids/benzodiazepines-opioids>
[4] Epilepsy Foundation. (n.d.). Treatment Options. Retrieved from <
https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/treatment-options>