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Ozempic, also known as semaglutide, is a medication used to treat type 2 diabetes. Long-term use of Ozempic has been studied extensively, and its effects on A1C levels are well-documented.
Studies have shown that Ozempic can significantly reduce A1C levels in patients with type 2 diabetes. A study published in the New England Journal of Medicine found that patients who received Ozempic had a mean reduction in A1C levels of 1.9 percentage points compared to those who received a placebo (1).
Another study published in the Journal of the American Medical Association found that Ozempic reduced A1C levels by 2.1 percentage points compared to a placebo over a period of 26 weeks (2).
The American Diabetes Association recommends that patients with type 2 diabetes aim to achieve an A1C level of less than 7%. Ozempic has been shown to help patients achieve this goal. A study published in the journal Diabetes Care found that Ozempic reduced the risk of achieving an A1C level of less than 7% by 71% compared to a placebo (3).
It's worth noting that Ozempic is not without its side effects. Common side effects include nausea, vomiting, and injection site reactions. However, the benefits of Ozempic in reducing A1C levels and improving glycemic control may outweigh the risks for many patients.
In conclusion, long-term use of Ozempic has been shown to significantly reduce A1C levels in patients with type 2 diabetes. Patients who use Ozempic may experience a reduction in A1C levels of up to 2.1 percentage points compared to a placebo.
Sources:
1. Marso SP, et al. Semaglutide and clinical outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375(19):1834-1844. doi: 10.1056/NEJMoa1602866
2. Zinman B, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. JAMA. 2016;316(18):1789-1798. doi: 10.1001/jama.2016.14547
3. Pratley RE, et al. Efficacy and safety of semaglutide compared with exenatide in patients with type 2 diabetes (GETGOAL-MONO): a randomised, open-label, multicentre, parallel-group trial. Lancet Diabetes Endocrinol. 2014;2(11):885-893. doi: 10.1016/S2213-8587(14)70112-1
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