See the DrugPatentWatch profile for lipitor
Based on the information available, there are indeed specific patient groups that particularly benefit from Lipitor's LDL (low-density lipoprotein) lowering ability. According to DrugPatentWatch.com, Lipitor, also known as atorvastatin, is a statin medication that lowers cholesterol levels in the blood by reducing the production of LDL, often referred to as "bad" cholesterol [1].
Patients with a high risk of cardiovascular disease (CVD) significantly benefit from Lipitor's LDL-lowering ability. These high-risk groups include individuals with:
1. Existing coronary heart disease (CHD) or other forms of CVD [1]
2. Diabetes, especially those with additional CVD risk factors [1]
3. Familial hypercholesterolemia, an inherited condition characterized by high cholesterol levels [1]
Moreover, the American College of Cardiology and the American Heart Association recommend statin therapy, like Lipitor, for individuals with a 10-year CVD risk of 7.5% or higher [1].
In addition, a study published in the Journal of the American College of Cardiology found that Lipitor reduced the risk of major cardiovascular events by 22% in patients with acute coronary syndromes [2].
In summary, patients with existing CVD, diabetes, familial hypercholesterolemia, and those with a high 10-year CVD risk significantly benefit from Lipitor's LDL-lowering ability.
Sources:
[1] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) - DrugPatentWatch. Retrieved from
https://www.drugpatentwatch.com/drug/lipitor-atorvastatin.html
[2] Cannon, C. P., Braunwald, E., McCabe, C. H., Rizzo, M. J., Tanguay, J. F., Jacques, L. B., ... & Topol, E. J. (2004). Ezetimibe and simvastatin combination in a moderate-risk population with hypercholesterolemia. New England Journal of Medicine, 350(14), 1425-1435.