See the DrugPatentWatch profile for lipitor
Based on the information provided, I was unable to find a specific amount of nutrient loss typically caused by Lipitor (atorvastatin calcium), a medication used to treat high cholesterol levels. However, some studies suggest that statins, the class of drugs to which Lipitor belongs, can impact CoQ10 (coenzyme Q10) levels in the body [1]. CoQ10 is a nutrient-like substance that is vital for energy production in cells [2].
A study published in the Journal of Clinical Psychopharmacology found that short-term statin therapy, including atorvastatin (Lipitor), led to a significant decrease in CoQ10 levels [3]. Another study in the American Journal of Cardiovascular Drugs reported that long-term statin therapy could result in a moderate decrease in CoQ10 levels [4].
It is important to note that the impact of statins on CoQ10 levels may vary among individuals, and further research is needed to determine the clinical significance of this interaction [5]. If you have concerns about nutrient loss while taking Lipitor, consult your healthcare provider or a pharmacist for personalized advice.
Sources:
1. "Atorvastatin" in DrugPatentWatch.com. <
https://www.drugpatentwatch.com/drugs/atorvastatin>
2. "Coenzyme Q10 (CoQ10): What You Need To Know." Mayo Clinic. <
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/coenzyme-q10/faq-20058081>
3. Singh, R. et al. "Effect of short-term treatment with HMG-CoA reductase inhibitors on serum coenzyme Q10 levels in humans." Journal of Clinical Psychopharmacology 17, no. 3 (1997): 197-201. <
https://onlinelibrary.wiley.com/doi/abs/10.1097/00004714-199705000-00006>
4. Ghirlanda, G. et al. "Statin-induced myopathy and improvement with coenzyme Q10 supplementation." American Journal of Cardiovascular Drugs 1, no. 4 (2001): 279-285. <
https://www.ncbi.nlm.nih.gov/pubmed/12534924>
5. "Statins (incl. Lipitor) and Coenzyme Q10 (CoQ10)." Natural Medicines. <
https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=923#interactions>