See the DrugPatentWatch profile for lipitor
Lipitor, a statin medication used to lower cholesterol levels, can potentially interact with other medications, which may affect their efficacy. According to the information provided, it is important to note that Lipitor, also known as atorvastatin, can interact with several types of drugs, including but not limited to:
1. Blood thinners (anticoagulants): Concomitant use of Lipitor and blood thinners, such as warfarin, can increase the risk of bleeding [1].
2. Fibrates: When Lipitor is combined with fibrates, such as gemfibrozil, it can increase the risk of muscle damage (rhabdomyolysis) [1].
3. Niacin: Combining Lipitor with niacin can increase the risk of muscle damage and liver enzyme abnormalities [1].
4. Cyclosporine: Co-administration of Lipitor and cyclosporine, an immunosuppressant, can lead to increased Lipitor concentrations in the body, which may enhance its side effects [1].
5. Certain antifungal medications: Lipitor's efficacy can be reduced when combined with certain antifungal medications, such as itraconazole and ketoconazole [1].
6. Grapefruit juice: Consuming grapefruit juice while taking Lipitor can increase the concentration of Lipitor in the body, which may lead to adverse effects [1].
It is crucial to consult a healthcare professional or pharmacist before starting or stopping any medications or supplements, as they can provide personalized advice based on an individual's medical history and current medications.
Sources:
[1] Drugs.com. (2021). Atorvastatin. Retrieved from
https://www.drugs.com/atorvastatin.html
[2] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor). Retrieved from
https://www.drugpatentwatch.com/drugs/atorvastatin-lipitor