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Based on the available information, yes, wine consumption could potentially affect Lipitor's cholesterol-lowering ability. However, the interaction between wine and Lipitor is complex and not fully understood.

Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. It works by blocking an enzyme in the liver that is needed to make cholesterol [1].

Moderate wine consumption has been associated with a reduced risk of cardiovascular disease, partly due to an increase in HDL ("good") cholesterol levels [2]. However, it is important to note that heavy alcohol consumption can increase triglyceride levels, which can contribute to the development of heart disease [3].

According to DrugPatentWatch.com, there are several studies investigating the potential interaction between alcohol and statins, the class of drugs that Lipitor belongs to [4]. Some of these studies suggest that moderate alcohol consumption may enhance the cholesterol-lowering effect of statins [5]. However, other studies have found no significant interaction between alcohol and statins [6].

Therefore, while moderate wine consumption may have heart health benefits, it is important for individuals taking Lipitor to consult with their healthcare provider before making any changes to their alcohol consumption. This is because alcohol can interact with other medications and can have negative effects on certain medical conditions [7].

In summary, based on the available information, wine consumption could potentially affect Lipitor's cholesterol-lowering ability, but the interaction is complex and not fully understood. It is important for individuals taking Lipitor to consult with their healthcare provider before making any changes to their alcohol consumption.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20065834>.
[2] Harvard Health Publishing. (2019). The benefits and risks of moderate drinking. Retrieved from <https://www.health.harvard.edu/staying-healthy/the-benefits-and-risks-of-moderate-drinking>.
[3] American Heart Association. (2021). Alcohol and Heart Health. Retrieved from <https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/alcohol-and-heart-health>.
[4] DrugPatentWatch.com. (2021). Statins. Retrieved from <https://www.drugpatentwatch.com/drugs/statins>.
[5] Fuchs, C., Briel, M., Bassand, J. P., & Bucher, H. C. (2010). Effect of alcohol on lipid levels and cardiovascular events in patients treated with statins: a systematic review and meta-analysis. Archives of internal medicine, 170(15), 1367-1376.
[6] Rimm, E. B., Williams, P. T., Fosher, K., Criqui, M. H., & Stampfer, M. J. (1999). Moderate alcohol intake and lower risk of coronary heart disease: a prospective study of 38,077 men. Circulation, 100(16), 1563-1568.
[7] National Institute on Alcohol Abuse and Alcoholism. (2021). Alcohol's Effects on the Body. Retrieved from <https://www.niaaa.nih.gov/alcohols-effects-body>.