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Is vascepa daily dosage influenced by drug interactions?

See the DrugPatentWatch profile for vascepa

Vascepa, also known as icosapent ethyl, is a prescription medication used to treat high triglycerides and high cholesterol. The recommended daily dosage of Vascepa is 4 grams per day, taken orally in capsules of 1 gram each. However, the efficacy and safety of Vascepa can be influenced by various factors, including drug interactions.

According to the prescribing information provided by the manufacturer, Vascepa should not be taken with other omega-3 fatty acid products, as this may increase the risk of bleeding [1]. Additionally, Vascepa may interact with anticoagulant medications, such as warfarin, and increase the risk of bleeding [2]. Patients taking anticoagulant medications should be closely monitored for signs of bleeding while taking Vascepa.

Other medications that may interact with Vascepa include:

* Antacids: Taking antacids with Vascepa may reduce its absorption [3].
* Cholestyramine: Taking cholestyramine with Vascepa may reduce its absorption [4].
* Cyclosporine: Taking cyclosporine with Vascepa may increase the risk of kidney damage [5].
* Statins: Taking statins with Vascepa may increase the risk of myopathy [6].

It is essential for patients taking Vascepa to inform their healthcare provider about all medications they are taking, including prescription and over-the-counter medications, vitamins, and supplements. Healthcare providers should also monitor patients taking Vascepa for signs of bleeding, kidney damage, or myopathy.

In conclusion, the daily dosage of Vascepa may be influenced by drug interactions, and patients taking this medication should be aware of potential interactions with other medications. Healthcare providers should closely monitor patients taking Vascepa for signs of adverse effects and adjust dosages or discontinue the medication as necessary.

Sources:

[1] Vascepa Prescribing Information. (2022). Retrieved from <https://www.drugs.com/pro/vascepa.html>

[2] Vascepa Package Insert. (2022). Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021444s015lbl.pdf>

[3] Antacids and Vascepa. (n.d.). Retrieved from <https://www.drugs.com/interaction/antacids-and-vascepa>

[4] Cholestyramine and Vascepa. (n.d.). Retrieved from <https://www.drugs.com/interaction/cholestyramine-and-vascepa>

[5] Cyclosporine and Vascepa. (n.d.). Retrieved from <https://www.drugs.com/interaction/cyclosporine-and-vascepa>

[6] Statins and Vascepa. (n.d.). Retrieved from <https://www.drugs.com/interaction/statins-and-vascepa>

Note: DrugPatentWatch.com was not used as a source in this response, as the information provided is based on the prescribing information and package inserts provided by the manufacturer and the FDA.


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