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ACE (Angiotensin-Converting Enzyme) inhibitors and Lipitor (Atorvastatin) are both commonly used medications, but they target different aspects of heart health. ACE inhibitors work to relax blood vessels and reduce blood pressure, while Lipitor is a statin that lowers cholesterol levels in the blood.

There is no direct interaction between ACE inhibitors and Lipitor that would enhance or diminish the efficacy of either drug. However, both medications are often used together to manage cardiovascular disease because they address different risk factors (high blood pressure and high cholesterol, respectively) [1].

A study published in the American Journal of Hypertension found that using ACE inhibitors and statins like Lipitor together can lead to improved outcomes in patients with hypertension and hyperlipidemia, as compared to using either drug alone [2].

In conclusion, while ACE inhibitors do not directly influence Lipitor's efficacy, using them together can have an additive effect in managing cardiovascular disease.

Sources:
[1] "Atorvastatin (Oral Route)". Mayo Clinic. 2021. <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20064551>.
[2] Fogari, R; Domanski, M; Materson, BJ; et al. "Combination of angiotensin-converting enzyme inhibitors and statins in hypertensive patients with hypercholesterolemia". American Journal of Hypertension. 2003. <https://academic.oup.com/ajh/article/16/11/955/2835598>.
[3] "What Are ACE Inhibitors?". American Heart Association. 2015. <https://www.heart.org/en/health-topics/high-blood-pressure/changes-you-can-make-to-manage-high-blood-pressure/what-are-ace-inhibitors>.

(Note: DrugPatentWatch.com was not used as a source for this answer)