See the DrugPatentWatch profile for tigecycline

There is limited information available on the specific consequences of tigecycline overdose on infection severity. Tigecycline is an antibiotic used to treat various types of bacterial infections, including complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia [1].

In general, overdosing on antibiotics can lead to a range of adverse effects, such as nausea, vomiting, and diarrhea [2]. However, there is no specific information available on how tigecycline overdose might affect infection severity.

It is worth noting that tigecycline has a wide therapeutic index, which means that the difference between a therapeutic dose and a toxic dose is relatively large [3]. This suggests that the risk of overdose and its potential consequences may be lower for tigecycline than for other antibiotics.

In summary, while there is limited information on the consequences of tigecycline overdose on infection severity, overdosing on antibiotics can lead to a range of adverse effects. Healthcare professionals should follow appropriate guidelines and recommendations for the use of tigecycline to minimize the risk of overdose and ensure safe and effective treatment.

Sources:

1. Tigecycline prescribing information. FDA. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021857s015lbl.pdf>
2. Antibiotic overdose. Mayo Clinic. <https://www.mayoclinic.org/diseases-conditions/antibiotic-overdose/symptoms-causes/syc-20371531>
3. Tigecycline. DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/tigecycline>